93553-81-2

Basic information

• Product Name: 2-(3,4-DICHLORO-PHENYL)-SUCCINIC ACID
• Synonyms: 2-(3,4-DICHLORO-PHENYL)-SUCCINIC ACID;2-(3,4-dichlorophenyl)butanedioic acid
• CAS NO: 93553-81-2
• Molecular Formula: C₁₀H₈Cl₂O₄
• Molecular Weight: 263.07
• Mol File: 93553-81-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 370.9°C at 760 mmHg
• Flash Point: 178.1°C
• Appearance: /
• Density: 1.555g/cm³
• Vapor Pressure: 3.7E-06mmHg at 25°C
• Refractive Index: 1.601
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(3,4-DICHLORO-PHENYL)-SUCCINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DICHLORO-PHENYL)-SUCCINIC ACID(93553-81-2)
• EPA Substance Registry System: 2-(3,4-DICHLORO-PHENYL)-SUCCINIC ACID(93553-81-2)

Safety Data

• Hazardous Substances Data: 93553-81-2(Hazardous Substances Data)

Usage

General Description

2-(3,4-Dichloro-phenyl)-succinic acid is a chemical compound that belongs to the class of phenylsuccinic acids, which are commonly used as intermediates in the synthesis of pharmaceuticals and agricultural chemicals. 2-(3,4-DICHLORO-PHENYL)-SUCCINIC ACID is a dicarboxylic acid with two chlorine atoms attached to the phenyl ring. It is synthesized through the reaction of succinic acid with 3,4-dichlorophenylacetic acid. This chemical is used as a building block in the synthesis of various pharmaceutical agents, herbicides, and insecticides. Its molecular structure and properties make it a versatile and valuable reagent in organic synthesis. Additionally, it has potential applications in the field of materials science and as a chiral building block in the production of biologically active compounds.

InChI:InChI=1/C10H8Cl2O4/c11-7-2-1-5(3-8(7)12)6(10(15)16)4-9(13)14/h1-3,6H,4H2,(H,13,14)(H,15,16)

Upstream product

• 6287-38-3 3,4-dichlorobenzaldehyde 
• 55417-50-0 ethyl 2-cyano-3-(3,4-dichlorophenyl)-prop-2-enecarboxylate 
• 1412409-44-9 3,4-dichlorophenyl-α,β-dicyanoethyl propionate 

Downstream Products

• 81199-25-9 3-(3,4-dichlorophenyl)succinimide 
• 81199-31-7 1-Amino-3-(3,4-dichloro-phenyl)-pyrrolidine-2,5-dione 
• 93553-60-7 4-[3-(3,4-Dichloro-phenyl)-2,5-dioxo-pyrrolidin-1-yl]-benzenesulfonamide 
• 157904-53-5 5,6-dichloroindan-1-carboxylic acid 

Relevant articles and documents

Synthesis of 5, 6-dichloroindan-1-acids and their tetrazolyl derivatives as analgesic and anti-inflammatory agents

Indan derivatives, namely, 5-(5′,6′-dichloroindan-1′-yl)- tetrazole (12a) and 5-(5′,6′-dichloroindan-1′-yl)- methyltetrazole (12b), were synthesized conveniently from 5,6-dichloroindan-1- carboxylic acid (9a) and 5,6- dichloroindan-1-acetic acid (9b), respectively, as potential analgesic and anti-inflammatory agents. The analgesic and anti-inflammatory properties of 9a, 9b, 12a and 12b were evaluated by the acetic acid induced writhing in Swiss albino mice and the carrageenan-induced rat paw edema models, respectively. Compounds 9a and 12a exhibited significant analgesic activity with the doses of 50 and 100 mg/kg body weight, comparable to that of the positive controls, phenylbutazone, indomethacin and aminopyrine. The anti-inflammatory potencies of 9a and 12a were also comparable to that of the positive control, phenylbutazone. Compounds 9b and 12b showed analgesic and anti-inflammatory activities, but were weaker than that of compounds 9a and 12a.