935534-38-6

Basic information

• Product Name: 2-(tert-Butyl-dimethylsilanyloxy)-1-(4-fluorophenyl)-ethanone
• Synonyms: 2-(tert-Butyl-dimethylsilanyloxy)-1-(4-fluorophenyl)-ethanone
• CAS NO: 935534-38-6
• Molecular Formula: C₁₄H₂₁FO₂Si
• Molecular Weight: 0
• Mol File: 935534-38-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(tert-Butyl-dimethylsilanyloxy)-1-(4-fluorophenyl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(tert-Butyl-dimethylsilanyloxy)-1-(4-fluorophenyl)-ethanone(935534-38-6)
• EPA Substance Registry System: 2-(tert-Butyl-dimethylsilanyloxy)-1-(4-fluorophenyl)-ethanone(935534-38-6)

Safety Data

• Hazardous Substances Data: 935534-38-6(Hazardous Substances Data)

Upstream product

• 231301-08-9 tert-butyl((1-(4-fluorophenyl)vinyl)oxy)dimethylsilane 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 366-78-9 α-acetoxy-4-fluoroacetophenone 
• 456-04-2 2-Chloro-4'-fluoroacetophenone 
• 163089-34-7 N-methoxy-N-methyl-2-(1,1,2,2-tetramethyl-1-silapropoxy)acetamide 
• 460-00-4 1-Bromo-4-fluorobenzene 

Downstream Products

• 1312719-09-7 (Rs,1S)-N-(2-(tert-butyldimethylsilyloxy)-1-(4-fluorophenyl)ethyl)-2-methylpropane-2-sulfinamide 
• 224434-01-9 (S)-1-(4-fluorophenyl)-2-hydroxyethylamine 
• 1312718-97-0 (Rs)-N-(2-(tert-butyldimethylsilyloxy)-1-(4-fluorophenyl)ethylidene)-2-methylpropane-2-sulfinamide 
• 1266548-97-3 ethyl (Z)-4-tert-butyldimethylsilyloxy-3-(4-fluorophenyl) but-2-enoate 
• 1266548-98-4 ethyl (E)-4-tert-butyldimethylsilyloxy-3-(4-fluorophenyl) but-2-enoate 
• 1266549-11-4 (4S)-3-[(Z)-6-tert-butyldimethylsilyloxy-5-(4-fluorophenyl)hex-4-enoyl]-4-phenyl-ox azolidin-2-one 
• 1266549-14-7 [4-[(Z,1S,2R)-6-tert-butyldimethylsilyloxy-1-(4-fluoroanilino)-5-(4-fluorophenyl)-2-[ (4S)-2-oxo-4-phenyl-oxazolidine-3-carbonyl]hex-4-enyl]phenyl] benzoate 
• 1266548-94-0 (3R,4S)-3-[(Z)-4-acetoxy-3-(4-fluorophenyl)-but-2-enyl]-4-(4-benzoyloxyphenyl)-1-( 4-fluorophenyl)azetidin-2-one 
• 1266548-99-5 (Z)-4-tert-butyldimethylsilyloxy-3-(4-fluorophenyl)but-2-en-1-ol 
• 1266549-01-2 tert-butyl-[(Z)-4-chloro-2-(4-fluorophenyl)but-2-enoxy]-dimethyl-silane 
• 1266549-03-4 dimethyl 2-[(Z)-4-tert-butyldimethylsilyloxy-3-(4-fluorophenyl)but-2-enyl]propanedioate 
• 1266549-05-6 (Z)-6-tert-butyldimethylsilyloxy-5-(4-fluorophenyl)-2-methoxycarbonyl-hex-4-enoic acid 
• 1266549-07-8 methyl (Z)-6-tert-butyldimethylsilyloxy-5-(4-fluorophenyl)hex-4-enoate 
• 1266549-09-0 (Z)-6-tert-butyldimethylsilyloxy-5-(4-fluorophenyl)hex-4-enoic acid 

Relevant articles and documents

Green organocatalytic α-hydroxylation of ketones

An efficient and green method for the α-hydroxylation of substituted ketones has been developed. This method includes the in situ conversion of various ketones into the corresponding silyl enol ethers and their oxidation to the corresponding α-hydroxy ketones. Two protocols have been established leading either to protected α-hydroxy carbonyls or free α-hydroxy ketones. Both procedures are easy to follow and lead to good to high yields for a variety of ketones.

AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF

Preparation of azetidinone compounds and medical use thereof are provided by the present invention. More particularly, azetidionne compounds, shown as formula (I), wherein R1, R2, R3, R4, R5and R