93554-80-4

Basic information

• Product Name: 2-aminobutanenitrile
• CAS NO: 93554-80-4
• Molecular Formula: C₄H₈N₂*ClH
• Molecular Weight: 84.1197
• Mol File: 93554-80-4.mol

Chemical Properties

• Boiling Point: 160.5°C at 760 mmHg
• Flash Point: 50.9°C
• Density: 0.914g/cm³
• Vapor Pressure: 2.38mmHg at 25°C
• Refractive Index: 1.434
• CAS DataBase Reference: 2-aminobutanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aminobutanenitrile(93554-80-4)
• EPA Substance Registry System: 2-aminobutanenitrile(93554-80-4)

Safety Data

• Hazardous Substances Data: 93554-80-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-aminobutanenitrile is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of antiviral and antifungal agents.
Used in Agrochemical Industry:
2-aminobutanenitrile is used as a precursor in the production of agrochemicals, playing a crucial role in the development of compounds that protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
2-aminobutanenitrile is used as a versatile precursor in organic synthesis for its ability to undergo various reactions, leading to the creation of a wide range of chemical compounds with diverse applications.

Upstream product

• 24731-32-6 2-<(trimethylsilyl)oxy>butanenitrile 
• 123-38-6 propionaldehyde 
• 53726-14-0 DL-2-aminobutanamide 

Downstream Products

• 4476-02-2 2-hydroxybutanenitrile 
• 4368-06-3 3-hydroxybutanenitrile 
• 1190-76-7 (Z)-2-butenenitrile 
• 4786-20-3 crotononitrile 
• 5500-21-0 cyclopropropanecarbonitrile 
• 4426-48-6 1,2-butanediamine 

Relevant articles and documents

Bis-morpholinophosphorylchloride, a novel reagent for the conversion of primary amides into nitriles

Bis-morpholinophosphorylchloride (Bmpc), in the presence of a base, is an efficient dehydrating agent for both aromatic and aliphatic primary amides, and gives corresponding nitriles under mild conditions in god yields and purity. During the reaction the enantiomeric integrity remains intact.

Prebiotically Plausible Organocatalysts Enabling a Selective Photoredox α-Alkylation of Aldehydes on the Early Earth

Organocatalysis is a powerful approach to extend and (enantio-) selectively modify molecular structures. Adapting this concept to the Early Earth scenario offers a promising solution to explain their evolution into a complex homochiral world. Herein, we present a class of imidazolidine-4-thione organocatalysts, easily accessible from simple molecules available on an Early Earth under highly plausible prebiotic reaction conditions. These imidazolidine-4-thiones are readily formed from mixtures of aldehydes or ketones in presence of ammonia, cyanides and hydrogen sulfide in high selectivity and distinct preference for individual compounds of the resulting catalyst library. These organocatalysts enable the enantioselective α-alkylation of aldehydes under prebiotic conditions and show activities that correlate with the selectivity of their formation. Furthermore, the crystallization of single catalysts as conglomerates opens the pathway for symmetry breaking.