935694-98-7

Upstream product

• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 89-25-8 edaravone 
• 67056-52-4 5-(β-hydroxyethyl)-3,4-dimethyl-1-phenylpyrano[2,3-c]pyrazol-6-one 

Downstream Products

• 67056-52-4 5-(β-hydroxyethyl)-3,4-dimethyl-1-phenylpyrano[2,3-c]pyrazol-6-one 

Relevant academic research and scientific papers

Condensation of N-3-substituted 5-pyrazolones with esters of β-keto acids. Synthesis of pyrano[2,3-c]pyrazol-6-ones

N-Substituted 5-pryazolones undergo thermal condensation with esters of β-keto acids, losing water and alcohol molecules, to form N-substituted pyrano[2,3-c]pyrazol-6-ones. The pyran ring in these products is readily cleaved by the action of alkali to give the corresponding salts of unsaturated acids. 2006 Springer Science+Business Media, Inc.