935749-19-2

Basic information

• Product Name: acetic acid 1-phenyl-buta-2,3-dienyl ester
• Synonyms: acetic acid 1-phenyl-buta-2,3-dienyl ester
• CAS NO: 935749-19-2
• Molecular Weight: 188.226
• Mol File: 935749-19-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: acetic acid 1-phenyl-buta-2,3-dienyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: acetic acid 1-phenyl-buta-2,3-dienyl ester(935749-19-2)
• EPA Substance Registry System: acetic acid 1-phenyl-buta-2,3-dienyl ester(935749-19-2)

Safety Data

• Hazardous Substances Data: 935749-19-2(Hazardous Substances Data)

Upstream product

• 104516-09-8 1-phenylbuta-2,3-dien-1-ol 
• 108-24-7 acetic anhydride 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 22665-30-1 allenylzinc bromide 
• 100-52-7 benzaldehyde 
• 75-36-5 acetyl chloride 

Downstream Products

• 1383470-61-8 C₂₄H₂₁N 
• 211996-14-4 acetic acid (E)-1-methylene-3-phenyl-allyl ester 

Relevant articles and documents

Regioselectivity Switch in Palladium-Catalyzed Allenylic Cycloadditions of Allenic Esters: [4+1] or [4+3] Cycloaddition/Cross-Coupling

The first Pd-catalyzed asymmetric allenylic [4+1] cycloaddition was successfully developed. Alternatively, tuning the Pd catalyst switched the reactivity toward an unprecedented [4+3] cycloaddition/cross-coupling. Ligands play a vital role in controlling the reaction pathway, allowing highly selective access to different products from identical substrates. Biological evaluation of the obtained compounds led to the discovery of new antitumor targets. A possible mechanism is proposed, suggesting two interesting catalytic cycles for the cycloaddition with palladium-butadienyls. This study also demonstrated the potential and utility of allenic esters as 1,4-biselectrophiles and C4 synthons for participating in cycloaddition reactions.

Highly stereoselective kinetic resolution of α-allenic alcohols: An enzymatic approach

A highly efficient lipase AK-catalyzed direct kinetic resolution of a variety of α-allenic alcohols was developed. With the complementary to previous studies, the current reaction system is effective on a broad range of substituents (R1) at C(1), such as alkyl, aryl, alkenyl, and alkynyl groups. The Jones-Burgess empirical model was modified to interpret the reversed selectivity during the acetylation of secondary alcohol. The methyl group at C(2) of allenic alcohols implied a small structural adjustment in the catalytic triad of lipase AK, representing a potential direction for future site-directed mutagenesis.

Highly stereoselective facile synthesisl of 2-acetoxy-1,3(E)-alkadienes via a Rh(I)-catalyzed isomerization of 2,3- allenyl carboxylates

A highly stereoselective Rh(I)-catalyzed 1,3-acetoxyl rearrangement of 1,2-allen-3-yl carboxylates leading to 2-acetoxy-1,3(E)-alkadienes has been developed. In addition to the high catalytic efficiency and the scope, the excellent E-selectivity of the do