935859-52-2

Upstream product

• 60531-36-4 4-(2-amino-ethyl)-benzoic acid hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 421551-76-0 tert-butyl N-{2-[4-(hydroxymethyl)phenyl]ethyl}carbamate 
• 1202890-07-0 4-(2-(tert-butoxycarbonylamino)ethyl)benzyl methanesulfonate 
• 124-40-3 dimethyl amine 
• 132690-91-6 4-[2-(tert-butyloxycarbonylamino)ethyl]benzoic acid 
• 929017-48-1 tert-butyl N-[2-[4-(dimethylcarbamoyl)phenyl]ethyl]carbamate 

Downstream Products

• 669002-47-5 2-(4-dimethylaminomethyl-phenyl)-ethylamine 
• 1202890-09-2 methyl 6-cyano-7-(4-(4-((dimethylamino)methyl)phenethylcarbamoyl)phenoxy)chroman-4-carboxylate 
• 1202887-25-9 6-cyano-7-(4-(4-((dimethylamino)methyl)phenethylcarbamoyl)phenoxy)chroman-4-carboxylic acid 
• 929017-59-4 5-[2-(4-dimethylaminomethyl-phenyl)-ethyl]-4-oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES

Compounds of Formula (I): in which A1, A2, W, L, G, R7a, R7b, R8, R9 and R10 have the meanings given in the specification, are DP2 receptor modulators useful in the treatment of immunologic diseases.

Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists

The synthesis and biological testing of novel classes of potent melanin-concentrating hormone (MCH-R1) antagonists based on pyrazolopiperazinone and pyrrolopiperazinone scaffolds are described.