93593-07-8

Upstream product

• 22261-94-5 N-(1-methyl-4-piperidinyl)aniline 
• 100-47-0 benzonitrile 
• 62-53-3 aniline 
• 1445-73-4 1-Methyl-4-piperidone 
• 99929-53-0 N-(1-methyl-4-piperidinyl)-3-phenylindole 

Downstream Products

• 93592-29-1 4-{(2-Benzoyl-phenyl)-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetyl]-amino}-piperidine-1-carboxylic acid benzyl ester 
• 93592-30-4 4-(2-Oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)-piperidine-1-carboxylic acid benzyl ester 
• 93592-28-0 4-(2-Benzoyl-phenylamino)-piperidine-1-carboxylic acid benzyl ester 
• 93592-17-7 1,3-dihydro-1-(1-ethoxycarbonyl-4-piperidinyl)-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 93591-79-8 1-(1-acetyl-4-piperidinyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 93592-71-3 1-(1-methyl-4-piperidinyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 93591-78-7 1-[4-(2-benzoylphenylamino)piperidin-1-yl]ethanone 
• 93592-27-9 2-benzoyl-N-(4-piperidinyl)aniline 
• 93592-26-8 N-<1-(ethoxycarbonyl)-4-piperidinyl>-2-benzoylaniline 

Relevant academic research and scientific papers

Ortho-mono-substituted amino)phenylimines

Novel ortho-(mono-substituted amino)phenylimines being intermediates to psychotropic drugs and other drugs are economically and industrially prepared by reacting anilines with nitriles in the presence of a boron trifluoride ether adduct and a halide-type

Aminohaloborane in Organic Synthesis. IX. Exclusive ortho Acylation Reaction of N-Monoaminoalkylanilines

The exclusive ortho acylation reaction of aniline derivatives using boron trichloride made possible the one-step synthesis of 2-acyl-N-monoaminoalkylanilines (1) and the corresponding imines (2) from N-monoaminoalkylanilines, even in the case of compounds with a bulky substituent at the nitrogen atom.Conventional methods only give 1 via elaborate procedures.Keywords: regioselective reaction; 2-acylaniline derivative; 2-acylaniline-imine derivative; boron trichloride

Aminohaloborane in Organic Synthesis. X. A Convenient, Economical Exclusive ortho Substitution Reaction of N-Alkyl and N-Aminoalkyl Anilines

A method for in situ generation of boron trichloride from boron trifluoride etherate and silicon tetrachloride in the presence of triethylamine, traced by boron-11 nuclear magnetic resonance (11B-NMR) spectroscopy, was successfully developed, thus elimina