936352-81-7

Upstream product

• 492465-50-6 4,6-bis{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}isophthalic acid 
• 52959-28-1 dimethyl 4,6-dihydroxyisophthalate 
• 874210-29-4 4,6-bis{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}isophthalic acid dimethyl ester 
• 62921-74-8 2-(2-(2-methoxyethoxy)ethoxy)ethyl p-toluenesulfonate 
• 936347-09-0 (5-(methoxycarbonylmethylcarbamoyl)-2,4-bis{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}benzoylamino)acetic acid methyl ester 
• 936352-98-6 5-amino-2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}benzoic acid methyl ester 

Downstream Products

• 936353-93-4 3-amino-5-tert-butoxycarbonylaminobenzoic acid 2-[2-(2-methoxyethoxy)ethoxy]ethyl ester 
• 936354-31-3 C₆₄H₉₆N₆O₂₆ 

Relevant academic research and scientific papers

Sequence-specific association in aqueous media by integrating hydrogen bonding and dynamic covalent interactions

Oligoamide strands that associate in a sequence-specific fashion into hydrogen-bonded duplexes in nonpolar solvents were converted into disulfide cross-linked duplexes in aqueous media. Thus, by incorporating trityl-protected thiol groups, which allows the reversible formation of disulfide bonds, into the oligoamide strands, only duplexes consisting of complementary hydrogen-bonding sequences were formed in aqueous solution as well as in methanol. The sequence-specific cross-linking of oligoamide strands was confirmed by MALDI-TOF, reverse-phase HPLC, and by isolating a cross-linked duplex. This study demonstrates that the sequence-specificity characteristic of multiply hydrogen-bonded systems can be extended into competitive media through the interplay of H-bonding and reversible covalent interactions, based on which a new class of molecular associating and ligating units that are compatible with both polar and nonpolar environments can be conveniently obtained. Copyright