93668-71-4Relevant academic research and scientific papers
One pot synthesis of α-ketoamides from ethylarenes and amines: a metal free difunctionalization strategy
Ramanathan, Mani,Kuo, Chun-Kai,Liu, Shiuh-Tzung
, p. 11446 - 11453 (2016)
One-pot and metal free synthesis of α-ketoamides has been described through in situ generation of aryl ketones from easily available ethylarenes followed by amidation with various amines. This multiple oxidation protocol involves catalytic I2-pyridine-TBHP (t-butyl hydroperoxide) mediated oxidative benzylic carbonylation and sequential NaI-TBHP mediated oxidative amidation without using any solvent.
N-[2-4-(1H-Imidazol-1-yl)alkyl]-arylamides and pharmaceutical compositions
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, (2008/06/13)
This disclosure describes novel N-[ω-(1H-imidazol-1-yl)alkyl]arylamides which possess the property of inhibiting the enzyme thromboxane synthetase and are also useful in the treatment of hypertension and myocardial ischemia.
