936691-38-2

Upstream product

• 936691-37-1 [1-benzyl-4-(tert-butyl-diphenyl-silanyloxy)-3-methyl-butyl]-carbamic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 936691-45-1 (2S,4R)-allyl 4-(2-((1R,3R)-1-acetoxy-3-((2S,3S)-N,3-dimethyl-2-((R)-1-methylpiperidine-2-carboxamido)pentanamido)-4-methylpentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate 
• 936691-44-0 (2S,4R)-allyl 4-(2-((1R,3R)-1-acetoxy-3-((2S,3S)-2-amino-N,3-dimethylpentanamido)-4-methylpentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate 
• 936691-43-9 allyl (2S,4R)-4-(2-((5S,8R,10R)-5-sec-butyl-1-(9H-fluoren-9-yl)-8-isopropyl-7-methyl-3,6,12-trioxo-2,11-dioxa-4,7-diazatridecan-10-yl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate 
• 936691-42-8 (2S,4R)-allyl 4-(2-((1R,3R)-1-acetoxy-4-methyl-3-(methylamino)pentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate 
• 936691-41-7 (2S,4R)-allyl 4-(2-((1R,3R)-1-acetoxy-3-((tert-butoxycarbonyl)(methyl)amino)-4-methylpentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate 
• 936691-40-6 C₁₅H₂₁NO₂ 
• 936691-39-3 allyl (2S,4R)-4-(bis(tert-butoxycarbonyl)amino)-2-methyl-5-phenylpentanoate 
• 936691-51-9 C₂₂H₃₃NO₆ 

Relevant academic research and scientific papers

Total synthesis of N14-desacetoxytubulysin H

Equation presented The N14-desacetoxy analogue of tubulysin H was prepared in 20 steps and 2.1% overall yield. Our strategy features a thiazole anion addition to assemble the tubuvaline residue at the C(10)-C(11) bond, as well as acylations at