937263-42-8

Basic information

• Product Name: 4-(imidazo[1,2-a]pyridin-7-yloxy)-3-methylaniline
• Synonyms: 4-(imidazo[1,2-a]pyridin-7-yloxy)-3-methylaniline
• CAS NO: 937263-42-8
• Molecular Formula: C₁₄H₁₃N₃O
• Molecular Weight: 239.27252
• EINECS: -0
• Mol File: 937263-42-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.25±0.1 g/cm3(Predicted)
• PKA: 6.54±0.50(Predicted)
• CAS DataBase Reference: 4-(imidazo[1,2-a]pyridin-7-yloxy)-3-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(imidazo[1,2-a]pyridin-7-yloxy)-3-methylaniline(937263-42-8)
• EPA Substance Registry System: 4-(imidazo[1,2-a]pyridin-7-yloxy)-3-methylaniline(937263-42-8)

Safety Data

• Hazardous Substances Data: 937263-42-8(Hazardous Substances Data)

Upstream product

• 937263-41-7 7-(2-methyl-4-nitrophenoxy)imidazo [1,2-a]pyridine 
• 896139-85-8 imidazo[1,2-a]pyridine-7-ol 
• 455-88-9 5-nitro-2-fluorotoluene 
• 864244-98-4 4-(2-methyl-4-nitrophenoxy)pyridin-2-amine 
• 33631-05-9 2-amino-4-hydroxypyridine 

Relevant articles and documents

[1,3]DIAZINO[5,4-d]PYRIMIDINES AS HER2 INHIBITORS

The present invention relates to new [1,3]diazino[5,4-d]pyrimidines and derivatives of Formula (I), wherein the groups R1, R2, R3 and R4 have the meanings given in the claims and specification, their use as inhibitors of HER2 and its mutants, pharmaceutical compositions which contain such compounds and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.

ERBB RECEPTOR INHIBITORS

Disclosed are compounds inhibiting ErbBs (e. g. HER2), pharmaceutically acceptable salts, hydrates, solvates or stereoisomers thereof and pharmaceutical compositions comprising the compounds. The compound and the pharmaceutical composition can effectively treat diseases associated ErbBs (especially HER2), including cancer.