93732-92-4Relevant academic research and scientific papers
Development of a diversity-oriented approach to oxazole-5-amide libraries
Thompson, Mark J.,Adams, Harry,Chen, Beining
experimental part, p. 3856 - 3865 (2009/09/29)
(Chemical Equation Presented) A highly versatile route to oxazole-5-amides is presented. Conversion of readily accessible oxazole-5-trifluoroacetamides into their Boc-protected 5-aminooxazole derivatives provides intermediates amenable to parallel amide s
Direct, facile synthesis of N-acyl-α-amino amides from α-keto esters and ammonia
Ntaganda, Rukundo,Milovic, Tamara,Tiburcio, Jorge,Thadani, Avinash N.
experimental part, p. 4052 - 4054 (2009/03/11)
N-Acyl-α-amino amides were prepared, without the necessity of chromatographic purification, in a single step by heating the corresponding α-keto ester in methanolic ammonia. The Royal Society of Chemistry.
Synthesis of 5-aminothiazoles as building blocks for library synthesis
Thompson, Mark J.,Heal, William,Chen, Beining
, p. 2361 - 2364 (2007/10/03)
A convenient route to 4-phenyl-5-aminothiazoles is described, which offers control over substitution at the 2-position. 2-N-Acylglycinamides were dithionated and a subsequent TFAA-mediated cyclisation step was followed by removal of the 5-N-trifluoroacety
