38093-77-5

Basic information

• Product Name: 2,4-diphenylthiazol-5-aMine
• Synonyms: 2,4-diphenylthiazol-5-aMine
• CAS NO: 38093-77-5
• Molecular Formula: C₁₅H₁₂N₂S
• Molecular Weight: 252.33418
• Mol File: 38093-77-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-diphenylthiazol-5-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-diphenylthiazol-5-aMine(38093-77-5)
• EPA Substance Registry System: 2,4-diphenylthiazol-5-aMine(38093-77-5)

Safety Data

• Hazardous Substances Data: 38093-77-5(Hazardous Substances Data)

Usage

General Description

2,4-diphenylthiazol-5-amine is a chemical compound with the molecular formula C17H13NS. It is a thiazole derivative, which is a class of organic compounds containing a five-membered ring with sulfur and nitrogen atoms. 2,4-diphenylthiazol-5-aMine has been synthesized and studied for its potential use in pharmaceutical and medicinal applications. Thiazole derivatives have been found to exhibit various biological activities, including antifungal, antimicrobial, and anti-inflammatory properties, making them of interest for drug development. Additionally, 2,4-diphenylthiazol-5-amine may also have potential for use in research and development of new materials and catalysts due to its unique molecular structure and properties.

Upstream product

• 905589-09-5 (2,4-diphenyl-1,3-thiazol-5-yl)carbamic acid tert-butyl ester 
• 2227-79-4 benzenecarbothioamide 
• 16750-42-8 2-amino-2-phenylacetonitrile 
• 100-52-7 benzaldehyde 
• 98-88-4 benzoyl chloride 
• 93732-92-4 N-(2-amino-2-oxo-1-phenylethyl)benzamide 
• 700-63-0 (R)-phenylglycine amide 
• 884860-69-9 N-(2,4-diphenyl-thiazol-5-yl)-2,2,2-trifluoro-acetamide 
• 53628-41-4 benzylidene-(2,4-diphenyl-thiazol-5-yl)-amine 
• 54167-93-0 (2,4-diphenyl-thiazol-5-yl)-carbamic acid benzyl ester 
• 54167-78-1 (1-chloro-2-oxo-2-phenyl-ethyl)-carbamic acid benzyl ester 

Downstream Products

• 940911-00-2 2,4-diphenyl-5-[N,N-bis(2-propylpentanoyl)amino]thiazole 

Relevant articles and documents

AMIDE COMPOUND

The present invention relate to a compound represented by the formula (I) or (II) wherein ring A is an optionally substituted ring (the ring should not be pyrrolidine, piperidine and piperazine), ring B is an optionally substituted aromatic ring, ring D is an optionally substituted ring, R1 and R2 are each independently a hydrogen atom or a substituent, R3 is a hydrogen atom or a C1-6 alkyl group, or R3 is bonded to ring A to form a non-aromatic ring, ring Aa is an optionally substituted aromatic hydrocarbon, Y is CH or N, Ra1 is an optionally substituted hydrocarbon group, and Ra2 and Ra3 are each independently a hydrogen atom or a substituent, or a salt thereof. The present invention provides a compound having a DGAT inhibitory activity, which is useful for the treatment or amelioration of diseases or pathologies caused by high expression or high activation of DGAT.

Synthesis of 5-aminothiazoles as building blocks for library synthesis

A convenient route to 4-phenyl-5-aminothiazoles is described, which offers control over substitution at the 2-position. 2-N-Acylglycinamides were dithionated and a subsequent TFAA-mediated cyclisation step was followed by removal of the 5-N-trifluoroacety