937396-37-7

Upstream product

• 39796-52-6 N-benzyl-2-aminoacetamide 
• 67-64-1 acetone 
• 19811-52-0 Boc-glycine-benzylamide 
• 20432-97-7 N-benzylglycinamide hydrochloride 

Downstream Products

• 937396-38-8 benzyl 3-benzyl-2,2-dimethyl-4-oxoimidazolidine-1-carboxylate 
• 1229567-38-7 1-benzyl-2,2-dimethyl-5-oxo-2,5-dihydro-1H-imidazole 3-oxide 
• 1438895-07-8 C₁₈H₁₈N₂O 
• 1438895-08-9 C₁₈H₁₇FN₂O 
• 1438895-09-0 C₁₈H₁₇FN₂O 
• 1438895-10-3 C₁₈H₁₇FN₂O 
• 1438895-11-4 C₁₉H₂₀N₂O 
• 1438895-12-5 C₁₉H₂₀N₂O 
• 1438895-13-6 C₁₉H₂₀N₂O 
• 1438895-14-7 C₁₉H₂₀N₂O₂ 
• 1438895-15-8 C₁₉H₂₀N₂O₂ 
• 1438895-16-9 C₁₉H₂₀N₂O₂ 
• 1438895-17-0 C₁₇H₁₇N₃O 
• 1438895-18-1 C₁₇H₁₇N₃O 

Relevant academic research and scientific papers

A novel method for the preparation of 4-arylimidazolones

A series of 4-arylimidazolones have been accessed via late-stage, palladium-mediated arylation of acetone- and cyclohexanone-derived 4-chloroimidazolones. The 4-chloroimidazolones were prepared via a novel rearrangement of the corresponding imidazolone N-

Formal olefination and acylaziridination of imidazolones

(Figure presented) The first formal olefination and acylaziridination of imidazolones were obtained by cycloaddition of cyclic nitrones with alkenes and alkynes, respectively.

IMIDAZOLIDINONE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to imidazolidinone compounds which are inhibitors of the beta- secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.