937804-30-3Relevant academic research and scientific papers
A study on chemical behaviors of some 4-pyrones synthesized by one-step reactions towards various amines
Sener, Ahmet,Eskinoba, Siddik,Bildirici, Ishak,Genc, Hasan,Kasimogullari, Rahmi
, p. 337 - 341 (2007)
(Chemical Equation Presented) Cycloaddition of acetylbenzoyl ketene generated in situ as an intermediate during one-step reaction between excess benzoylacetone and oxalylchloride to C=C double bond of cyclic enol form of benzoylacetone gave 3-acetyl-5-benzoyl-6-methyl-2-phenyl-4(47Y)-pyrone 1a. Condensation reactions of 1a together with 3,5-dibenzoyl-2,6-diphenyl-4(4H)- pyrone 1b and 3-benzoyl-5-ethoxycarbonyl-2,6-diphenyl-4(4H)-pyrone 1c with two-fold excess primary amines provided a series of 3-benzoyl-1-alkyl-5-(1- alkylimino-ethyl)-6-phenyl-2-methyl-4(1H)-pyridinone 2, 3,5-dibenzoyl-1-alkyl-2, 6-diphenyl-4(1H)-pyridinone 3a-c and 3-benzoyl-1-alkyl-5-ethoxycarbonyl-2,6- diphenyl-4(1H)-pyridinone 3d,e derivatives, respectively. In addition, while prolonged reaction of n-pentylamine with unsymmetrical pyrone derivative la gives a symmetrical pyridinone derivative namely 3,5-dibenzoyl-2,6-dimethyl-1- pentyl-4(1H)-pyridinone 5, much prolonged action n-pentylamine and then aqueous n-pentylamine on 1b resulted in degradation of the 4-pyrone ring to give dibenzoylmethane.
