93799-43-0Relevant articles and documents
Preparation method of N,N-diethyl-2-hydroxyl-2-phenylacetamide
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Paragraph 0104; 0105; 0106; 0107-0115, (2019/05/08)
The invention provides a synthesis method of N,N-diethyl-2-hydroxyl-2-phenylacetamide. The N,N-diethyl-2-hydroxyl-2-phenylacetamide is obtained by condensing mandelic acid, serving as a raw material,with N-hydroxysuccinimide, and then performing substitut
Reactions of α-Hydroxy Carbonyl Compounds with Azodicarboxylates and Triphenylphosphine: Synthesis of α-N-Hydroxy Amino Acid Derivatives
Kolasa, Teodozyj,Miller, Marvin J.
, p. 4978 - 4984 (2007/10/02)
Reaction of aliphatic α-hydroxy esters with azodicarboxylates and triphenylphosphine in the presence of either CbzNHOCH2Ph or trOCNHOCH2Ph provides a direct route to protected α-N-hydroxy amino acids.Similar reactions with aromatic α-hydroxy carbonyl compounds and derivatives result in predominate oxidation to the corresponding α-oxo carbonyl derivatives.