938447-20-2

Upstream product

• 938447-12-2 3-[(E)-3-({1-[(2,5-dimethoxyphenyl)sulfonyl]piperidin-4-yl}amino)prop-1-enyl]benzonitrile 
• 36239-09-5 ethyl chlorocarbonylacetate 

Relevant academic research and scientific papers

Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors

We describe here our investigation of a new series of orally active fXa inhibitors based on a prodrug strategy. Solid-phase parallel synthesis identified a unique series of fXa inhibitors with a substituted benzenesulfonyl group as a novel S4 binding elem