93877-49-7

Upstream product

• 933-88-0 ortho-toluoyl chloride 
• 142626-67-3 2-benzyloxy-1-bromo-5,6,7,8-tetrahydronaphthalene 
• 32337-86-3 1-bromo-5,6,7,8-tetrahydronaphthalen-2-ol 
• 142626-68-4 1-bromo-3-(2-methylbenzoyl)-5,6,7,8-tetrahydro-2-naphthol 

Downstream Products

• 1025875-49-3 3-Isocyanato-4-o-tolyl-6,7,8,9-tetrahydro-benzo[g]chromen-2-one 
• 142626-70-8 4-(2-methylphenyl)-2-oxo-6,7,8,9-tetrahydro-2H-naphtho[2,3-b]pyran-3-carboxylic acid 
• 142626-69-5 ethyl 4-(2-methylphenyl)-2-oxo-6,7,8,9-tetrahydro-2H-naphtho[2,3-b]pyran-3-carboxylate 

Relevant academic research and scientific papers

Synthesis of 3-ureido derivatives of coumarin and 2-quinolone as potent Acyl-CoA: Cholesterol acyltransferase inhibitors

Novel 3-ureido derivatives of 4-phenylcoumarin and 4-phenyl-2-quinolone were synthesized and evaluated for acyl-CoA: cholesterol acyltransferase (ACAT)-inhibitory activity. These derivatives inhibited rat intestinal ACAT with IC50 values at the 10-8 to 10-9 M level and were found to normalize plasma cholesterol levels in cholesterol-fed rats when administered as dietary admixtures.

Certain 2-oxo-tetrahydro-cycloalkyl-benzopyran-3yl ureas having acyl-CoA-cholesterol acyl transferase inhibitory activity

Novel heterocyclic compound of the general formula: STR1 wherein ring A and ring B each means a benzene ring which is substituted or unsubstituted; X means a group of the formula: STR2 wherein R2 is hydrogen, an alkyl or an alkoxy; m is 0 or 1,