939968-60-2

Basic information

• Product Name: 3-Fluoro-4-nitrophenylboronic acid,pinacol ester
• Synonyms: 4-Fluoro-3-nitrobenzeneboronic acid pinacol ester, 96%;3-Fluoro-4-nitrobenzeneboronic acid pinacol ester, 96%;2-(3-Fluoro-4-nitrophenyl);3-Fluoro-4-nitrophenylboronic acid,pinacol ester;2-(3-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 939968-60-2
• Molecular Formula: C₁₂H₁₅BFNO₄
• Molecular Weight: 267.063
• Mol File: 939968-60-2.mol

Chemical Properties

• Appearance: Yellow/Crystalline Solid
• CAS DataBase Reference: 3-Fluoro-4-nitrophenylboronic acid,pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluoro-4-nitrophenylboronic acid,pinacol ester(939968-60-2)
• EPA Substance Registry System: 3-Fluoro-4-nitrophenylboronic acid,pinacol ester(939968-60-2)

Safety Data

• Hazardous Substances Data: 939968-60-2(Hazardous Substances Data)

Usage

Uses

3-Fluoro-4-nitrophenylboronic acid, pinacol ester

Upstream product

• 321-23-3 4-bromo-2-fluoronitrobenzene 
• 73183-34-3 bis(pinacol)diborane 
• 2369-13-3 3-fluoro-4-nitroaniline 

Downstream Products

• 1029529-08-5 5-(3-fluoro-4-nitrophenyl)-6-(4-fluorophenyl)-imidazo[2,1-b]oxazole 
• 1374110-19-6 C₁₅H₉FN₂O₂ 
• 1374110-20-9 C₁₅H₁₀N₂O₃ 
• 1374110-21-0 C₂₄H₂₉FN₂O₄Si 
• 1374110-22-1 C₂₄H₃₁FN₂O₂Si 
• 819058-34-9 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 
• 1565857-77-3 (2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)trimethylstannane 

Relevant articles and documents

NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF

The present invention relates to novel hydrazone derivatives in which a terminal amine group is substituted with an aryl group or a heteroaryl group, and uses thereof.

Novel hydrazone derivatives comprising aryl or heteroaryl group substituted at terminal amine and use thereof

The present invention relates to novel hydrazone derivatives with an aryl or heteroaryl group substituted at a terminal amine group thereof and a use thereof.

HETEROCYCLIC COMPOUND

The present invention provides a heterocyclic compound having a CDK8 and/or CDK19 inhibitory effect. The present invention provides a compound represented by formula (I) (in the formula, the symbols are as defined in the description) or a salt thereof.

Heterocyclic compound

本發明提供一種具有CDK8/19抑制活性之雜環化合物。本發明提供一種如下式代表之化合物(其中各代號均如本文之定義)或其鹽。 The present invention provides a heterocyclic compound possessing CDK8/19 inhibitory activity. The present invention provides a compound represented by the formula wherein each symbol is as defined herein, or a salt thereof.

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

Synthesis of trimethylstannyl arylboronate compounds by sandmeyer-type transformations and their applications in chemoselective cross-coupling reactions

A synthetic method based on Sandmeyer-type reactions to access both tin- and boron-substituted arenes from nitroaniline derivatives is described. This transformation can be applied to the synthesis of a series of functionalized trimethylstannyl arylboronates. In addition, the chemoselective reaction of the Stille and Suzuki-Miyaura cross-coupling reactions is explored, and a series of m- and p-terphenyl derivatives have been synthesized by conducting consecutive one-pot Stille and Suzuki-Miyaura cross-coupling reactions.

NOVEL IMIDAZOTHIAZOLES AND IMIDAZOXAZOLES

The present invention is directed to novel compounds of formula (I) wherein the variables are as defined herein. The compounds of formula (I) are useful as kinase inhibitors and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers.