940391-41-3Relevant academic research and scientific papers
Design, synthesis and evaluation of small molecule imidazo[2,1-b][1,3,4]thiadiazoles as inhibitors of transforming growth factor-β type-I receptor kinase (ALK5)
Patel, Harun M.,Sing, Baljeet,Bhardwaj, Varun,Palkar, Mahesh,Shaikh, Mahamadhanif S.,Rane, Rajesh,Alwan, Wesam S.,Gadad, Andanappa K.,Noolvi, Malleshappa N.,Karpoormath, Rajshekhar
, p. 599 - 613 (2015)
A new series of imidazo[2,1-b][1,3,4]thiadiazoles 5(a-g), 6(a-g), 9(a-i) and 12(a-h) were synthesized as transforming growth factor-β (TGF-β) type I receptor (also known as activin receptor-like kinase 5 or ALK5) inhibitors. These compounds were evaluated
Synthesis and anticancer evaluation of novel 2-cyclopropylimidazo[2,1-b][1, 3,4]-thiadiazole derivatives
Noolvi, Malleshappa N.,Patel, Harun M.,Singh, Navjot,Gadad, Andanappa K.,Cameotra, Swaranjit Singh,Badiger, Arvind
experimental part, p. 4411 - 4418 (2011/11/06)
A series of 2,5,6-trisubstituted imidazo[2,1-b][1,3,4]-thiadiazole derivatives 4(a-k) have been prepared by reaction of 2-amino-5-cyclopropyl-1,3, 4-thiadiazole and an appropriate phenacyl bromide. Further 5-bromo 5(a-k) and 5-thiocyanato 6(a-k) derivativ
