94079-25-1

Upstream product

• 65-85-0 benzoic acid 
• 82343-51-9 ethyl 3-methyl-5-oxo-5-phenyl-2-pentenoate 
• 98-88-4 benzoyl chloride 
• 4467-30-5 4-methyl-6-phenyl-2H-pyran-2-one 

Downstream Products

• 94079-27-3 4-Methyl-6-phenyl-2H-thiopyran-2-on 
• 83469-48-1 2-(4-Methyl-6-phenyl-2H-thiopyran-2-yliden)-1-phenylethanthion 
• 94079-05-7 4-Methyl-6-phenyl-2H-thiopyran-2-thion 
• 94079-11-5 2-(4-Methyl-6-phenyl-2H-thiopyran-2-yliden)-1-phenylethanon 
• 94079-09-1 4-Methyl-2-methylthio-6-phenylthiopyryliumiodid 
• 94079-07-9 4-Methyl-2-(2-phenyl-2-oxoethyl)thio-6-phenylthiopyryliumbromid 

Relevant academic research and scientific papers

Crystallographic investigation and selective inhibition of mutant isocitrate dehydrogenase

Mutations in isocitrate dehydrogenase (IDH), a key enzyme in the tricarboxylic acid cycle, have recently been found in ～75% glioma and ～20% acute myeloid leukemia. Different from the wild-type enzyme, mutant IDH1 catalyzes the reduction of α-ketoglutaric