941283-06-3Relevant academic research and scientific papers
Preparation of 6-substituted quinoxaline JSP-1 inhibitors by microwave accelerated nucleophilic substitution
Zhang, Li,Qiu, Beiying,Li, Xin,Wang, Xin,Li, Jingya,Zhang, Yongliang,Liu, Jian,Li, Jia,Shen, Jingkang
, p. 988 - 999 (2007/10/03)
A small library of 6-aminoquinoxalines has been prepared by nucleophilic substitution of 6-fluoroquinoxaline with amines and nitrogen-containing heterocycles under computer-controlled microwave irradiation. Some compounds were found to be potent inhibitors of JNK Stimulatory Phosphatase-1 (JSP-1) in an in vitro biological assay.
