941306-58-7

Basic information

• Product Name: Methyl 5-ethoxypicolinate
• Synonyms: Methyl 5-ethoxypicolinate
• CAS NO: 941306-58-7
• Molecular Formula: C9H11NO3
• Molecular Weight: 181.18854
• Mol File: 941306-58-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 5-ethoxypicolinate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-ethoxypicolinate(941306-58-7)
• EPA Substance Registry System: Methyl 5-ethoxypicolinate(941306-58-7)

Safety Data

• Hazardous Substances Data: 941306-58-7(Hazardous Substances Data)

Usage

Description

Methyl 5-ethoxypicolinate is a versatile chemical compound that consists of a methyl group, a 5-ethoxy group, and a picolinate group. It is widely used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals due to its unique chemical structure and reactivity.

Uses

Used in Pharmaceutical Industry:
Methyl 5-ethoxypicolinate is used as a key intermediate for the development of new drugs. Its ethoxy group attached to the picolinate ring makes it a valuable building block in the synthesis of various heterocyclic compounds, which are essential in the creation of innovative pharmaceutical products.
Used in Agricultural Industry:
Methyl 5-ethoxypicolinate is used as a crucial component in the production of pesticides and herbicides. Its unique chemical properties allow it to be incorporated into effective formulations that help protect crops and enhance agricultural productivity.

Upstream product

• 30766-12-2 methyl 5-hydroxypicolinate 
• 75-03-6 ethyl iodide 
• 2648-49-9 2-ethoxyprop-2-enal 
• 941306-53-2 2-ethoxyprop-2-enal dimethylhydrazone 
• 941306-56-5 methyl 1-dimethylamino-5-ethoxy-1,2,3,4-tetrahydropyridin-2-carboxylate 

Downstream Products

• 98353-08-3 5-ethoxypicolinic acid 

Relevant articles and documents

Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II

Tankyrase 1 and 2 (TNKS1/2) catalyze post-translational modification by poly-ADP-ribosylation of a plethora of target proteins. In this function, TNKS1/2 also impact the WNT/β-catenin and Hippo signaling pathways that are involved in numerous human diseas

Synthesis of 2-ethoxyprop-2-enal dimethylhydrazone and its Diels-Alder reactions

Conditions were found for the preparation of 2-ethoxyprop-2-enal dimethylhydrazone by reaction of 2-ethoxypropenal with N,N-dimethylhydrazine. 2-Ethoxyprop-2-enal dimethylhydrazone reacted with methyl vinyl ketone and methyl acrylate according to the [4 + 2]-cycloaddition pattern with regioselective formation of substituted tetrahydropyridines. The major product in the reaction of 2-ethoxyprop-2-enal dimethylhydrazone with 1,4-benzoquinone was 5-hydroxy-1-benzofuran-2-carbaldehyde dimethylhydrazone formed as a result of [3 + 2]-cycloaddition; a small amount of the corresponding [4 + 2]-cycloaddition product was also obtained. Some spontaneous transformations of the primary cycloaddition products were revealed.