941599-85-5Relevant academic research and scientific papers
Small molecule antagonists of the CC chemokine receptor 4 (CCR4)
, p. 3141 - 3145 (2007)
The identification, optimization, and structure-activity relationship (SAR) of small-molecule CCR4 antagonists is described. An initial screening hit with micromolar potency was identified that was optimized to sub-micromolar binding potency by enantiomer
