Bioorganic and Medicinal Chemistry Letters p. 3141 - 3145 (2007)
Update date:2022-07-30
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The identification, optimization, and structure-activity relationship (SAR) of small-molecule CCR4 antagonists is described. An initial screening hit with micromolar potency was identified that was optimized to sub-micromolar binding potency by enantiomer
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(2007)
