941609-28-5Relevant academic research and scientific papers
Trapping of Transient Thienyllithiums Generated by Deprotonation of 2,3-or 2,5-Dibromothiophene in a Flow Microreactor
Okano, Kentaro,Yamane, Yoshiki,Nagaki, Aiichiro,Mori, Atsunori
, p. 1913 - 1918 (2020)
Selective trapping of (4,5-dibromo-2-thienyl)lithium, known to undergo halogen dance, was achieved in a flow microreactor. This transient thienyllithium, generated by mixing 2,3-dibromothiophene and lithium diisopropylamide at-78 °C for 1.6 seconds, react
Synthesis of structurally diverse diarylketones through the diarylmethyl sp3 C-H oxidation
He, Chao,Zhang, Xiaohui,Huang, Ruofeng,Pan, Jing,Li, Jiaqiang,Ling, Xuege,Xiong, Yan,Zhu, Xiangming
supporting information, p. 4458 - 4462 (2014/08/05)
Under open-flask conditions, an efficient method to assemble a series of diversely functionalized diarylketones in the presence of commercially available NBS has been developed. Yields of up to 99% have been achieved employing diarylmethanes as starting material. Based on 18O-labeled experiment, the addition of stoichiometric water eventually leads to excellent yields in all carbonylation cases.
