94191-22-7

Upstream product

• 109-65-9 1-bromo-butane 
• 57402-97-8 N-<(trimethylsilyl)methyl>benzaldimine 
• 624-49-7 dimethylfumarate 
• 90606-10-3 (E)-N-(phenylmethylene)-1-(trimethylsilyl)methylamine 
• 542-69-8 1-iodo-butane 
• 778-28-9 butyl para-toluenesulfonate 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 136912-53-3 1-butyl-2-phenylaziridine 
• 82959-82-8 (3R,4R)-2-Phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

[3+2] Cycloadditions and nucleophilic additions of aziridines under C-C and C-N bond cleavage

Under PET conditions (photoinduced electron transfer) aziridines react with dipolarophiles in a [3+2] cycloaddition to form five-membered heterocycles. In this study we used mono- and disubstituted N-alkyl and N-arylaziridines. We noticed that the radical

One-Pot Synthesis of N-Alkylpyrrolidines by 1,3-Dipolar Cycloaddition

N-Alkylpyrrolidines were obtained by one-pot synthesis through 1,3-dipolar cycloaddition of the N-alkylazomethine ylide intermediates generated from N-(benzylidene)trimethylsilylmethylamine and alkyl halide or tosylate.

1,3-DIPOLAR CYCLOADDITION LEADING TO N-ALKYLPYRROLIDINES

1,3-Dipolar cycloaddition of an intermediary methyleneiminium ylide formed from N-(benzylidene)trimethylsilylmethylamine and alkyl halide to conjugated olefinic dipolarophiles has been found to give N-alkylpyrrolidines.KEYWORDS - N-alkylpyrrolidine; N-unsubstituted pyrrolidine; 1,3-dipolar cycloaddition; N-alkyltrimethylsilylmethyliminium salt; methyleneiminium ylide