57402-97-8Relevant articles and documents
NK1 ANTAGONIST
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Page/Page column 94, (2010/02/09)
The invention is to a compound exhibiting neurokinin inhibitory properties, a pharmaceutical composition comprising same and a method of treatment for neurokinin-meditated conditions.Formula (I)
AZOMETHINE YLIDE PRECURSORS: A SIMPLE ROUTE TO N-(TRIMETHYLSILYLMETHYL) IMINES
Letellier, M.,McPhee, D. J.,Griller, D.
, p. 1975 - 1978 (2007/10/02)
A simple synthesis of N-(trimethylsilylmethyl)amine is reported.This compounds was used to prepare N-(trimethylsilylmethyl)amines, useful sources of "nonstabilized" azomethine ylides.
1,3-Dipolar Cycloaddition Leading to N-Acylated Pyrrolidines and 2,5-Dihydropyrroles
Achiwa, Kazuo,Motoyama, Tadashi,Sekiya, Minoru
, p. 3939 - 3945 (2007/10/02)
Dipolar cycloaddition of an intermediary N-acyltrimethylsilylmethyliminium salt formed from N-(benzylidene)trimethylsilylmethylamine and acyl chloride to conjugated alkenes or alkines gave N-acylpyrrolidines or N-acyl-2,5-dihydropyrroles, respectively.The