942060-21-1Relevant articles and documents
A novel and facile synthesis of 1,4,5-trisubstituted 1,2,3-triazoles from benzylic alcohols through a one-pot, three-component system
González-Calderón, Davir,Santillán-Iniesta, Itzel,González-González, Carlos A.,Fuentes-Benítes, Aydeé,González-Romero, Carlos
, p. 514 - 516 (2015)
A simple one-pot procedure has been developed to efficiently prepare 1,4,5-trisubstituted 1,2,3-triazoles from benzylic alcohols. The presence of diphenylphosphoryl azide (DPPA) and active ketones allows for an azide-enolate [3+2] cycloaddition by use of DBU.
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
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, (2014/08/19)
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.