942203-08-9

Upstream product

• 849919-57-9 (2RS)-2-benzyl-1-benzyloxycarbonyl-2-carboxylazetidine 
• 61275-22-7 L-alanine-N-methylamide hydrochloride 
• 501-53-1 benzyl chloroformate 
• 849919-50-2 2-benzyl-2-(1-tert-butoxycarbonyl-ethylcarbamoyl)-azetidine-1-carboxylic acid benzyl ester 
• 849919-56-8 (2RS)-2-benzyl-1-benzyloxycarbonyl-2-metoxycarbonylazetidine 
• 33194-35-3 (S)-2-amino-N-methyl-propionamide 

Relevant academic research and scientific papers

Azetidine-derived amino acids versus proline derivatives. Alternative trends in reverse turn induction

(Figure Presented) The influence of 2-alkyl-2-carboxyazetidines (Aze) on the 3D structure of model tetrapeptides R2CO-2-R1Aze-L- Ala-NHMe has been analyzed by molecular modeling, 1H NMR, and FT-IR studies. The conformation

2-Alkyl-2-carboxy-azetidines as scaffolds for the induction of γ-turns

To investigate the ability of 2-alkyl-2-carboxy-azetidines (Azx) to induce reverse turns when incorporated into peptides, RCO-Azx-l-Ala-NHMe dipeptide derivatives were selected as simplified tetrapeptide models, in which the azetidine residue is incorpora

From 1-acyl-β-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors

Starting from the structure of known β-lactam covalent human cytomegalovirus (HCMV) protease inhibitors and from the knowledge of the residues implicated in the active site of this enzyme, we designed a series of phenylalanine-derived 2-azetidinones beari