942273-26-9Relevant academic research and scientific papers
Condensed-cyclic compound and organic light emitting diode comprising the same
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Paragraph 0395; 0399-0400, (2016/11/24)
Disclosed are a condensed-ring compound and an organic light-emitting device comprising the same. The condensed-ring compound is represented by chemical formula 1. The organic light-emitting device comprising the condensed-ring compound can have low driving voltage, high efficiency, high brightness, and long durability.COPYRIGHT KIPO 2016
SUBSTITUTED BENZENE COMPOUNDS
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Page/Page column 434-435, (2012/11/06)
The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
Aryl- or Heteroaryl-Substituted Benzene Compounds
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Page/Page column 174, (2012/10/23)
The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
Preparation of novel anthranilic acids as antibacterial agents. Extensive evaluation of alternative amide bioisosteres connecting the A- and the B-rings
Thorarensen, Atli,Wakefield, Brian D.,Romero, Donna L.,Marotti, Keith R.,Sweeney, Michael T.,Zurenko, Gary E.,Rohrer, Douglas C.,Han, Fusen,Bryant Jr., Garold L.
, p. 2823 - 2827 (2008/02/05)
In the past few years, a significant effort has been devoted by Pharmacia toward the discovery of novel antibiotics. We have recently described the identification of an anthranilic acid lead 1 and the optimization resulting in the advanced lead 2. In this report, we describe the preparation of several selected amide bioisosteres connecting the A- and the B-rings. The E-alkene provided a rigid analog with equal potency to the corresponding amide. This indicates that the amide is not a recognition element rather acts as an appropriate spatial linker of the two important aryl A and B rings. The work here clearly demonstrates that the amide linker can be replaced with several functionalities without significant deterioration in the MIC activity.
