942599-73-7

Basic information

• Product Name: [1-(3,5-bis-trifluoromethyl-phenyl)-ethoxy]-acetic acid tert-butyl ester
• Synonyms: [1-(3,5-bis-trifluoromethyl-phenyl)-ethoxy]-acetic acid tert-butyl ester
• CAS NO: 942599-73-7
• Molecular Weight: 372.308
• Mol File: 942599-73-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1-(3,5-bis-trifluoromethyl-phenyl)-ethoxy]-acetic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(3,5-bis-trifluoromethyl-phenyl)-ethoxy]-acetic acid tert-butyl ester(942599-73-7)
• EPA Substance Registry System: [1-(3,5-bis-trifluoromethyl-phenyl)-ethoxy]-acetic acid tert-butyl ester(942599-73-7)

Safety Data

• Hazardous Substances Data: 942599-73-7(Hazardous Substances Data)

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 368-63-8 (R)-[3,5-bis(trifluoromethyl)phenyl]ethanol 

Downstream Products

• 444020-12-6 [1-(3,5-bis-trifluoromethyl-phenyl)-ethoxy]-acetic acid 2-(tert-butyl-dimethyl-silanyloxymethyl)-3-phenyl-allyl ester 
• 444020-51-3 [1-(3,5-bis-trifluoromethyl-phenyl)-ethoxy]-acetyl chloride 

Relevant articles and documents

Stereoselective synthesis of a potent human NK1 receptor antagonist via acyl-Claisen rearrangement

Stereoselective synthesis of the tetrahydropyran derivative 1 is reported. Diastereoselective acyl-Claisen rearrangement was employed for formation of C3 and C4 chiral centres on the tetrahydropyran ring. Georg Thieme Verlag Stuttgart.