942625-95-8

Basic information

• Product Name: 1-(trimethylsiloxy)-1-o-chloro-phenylethene
• Synonyms: 1-(trimethylsiloxy)-1-o-chloro-phenylethene
• CAS NO: 942625-95-8
• Molecular Weight: 226.778
• Mol File: 942625-95-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-(trimethylsiloxy)-1-o-chloro-phenylethene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(trimethylsiloxy)-1-o-chloro-phenylethene(942625-95-8)
• EPA Substance Registry System: 1-(trimethylsiloxy)-1-o-chloro-phenylethene(942625-95-8)

Safety Data

• Hazardous Substances Data: 942625-95-8(Hazardous Substances Data)

Upstream product

• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 133662-20-1 1-(2-chlorophenyl)-2-hydroxyethanone 
• 40018-25-5 2-Chlorobenzoyl acetonitrile 
• 945612-77-1 2-(2-(2-chlorophenyl)-2-oxoethyl)benzo[d]isothiazol-3(2H)-one 1,1-dioxide 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 10268-06-1 2-(2-chlorophenyl)acetamide 
• 1360260-54-3 1-(2-chlorophenyl)-2-(2-phenyl-1,2,3,4-tetrahydroisoquinolin-1-yl)ethanone 
• 1338062-39-7 N-(2-(2-chlorophenyl)-2-oxoethyl)-4-methylbenzenesulfonamide 
• 1174147-62-6 C₂₇H₃₆ClNO₄Si 

Relevant articles and documents

Palladium-Catalyzed [5 + 2] Annulation of Vinylethylene Carbonates with Barbiturate-Derived Alkenes

A palladium/XantPhos-catalyzed [5 + 2] annulation of VECs with electron-deficient alkenes having an isolated carbon-carbon double bond has been developed to afford spirobarbiturate-tetrahydrooxepines. This study provides an expedient assembly of biologically interesting spirobarbiturate-tetrahydrooxepines. The easy scalability and versatile transformability of the reaction products were also exhibited.

C?O coupling of Malonyl Peroxides with Enol Ethers via [5+2] Cycloaddition: Non-Rubottom Oxidation

Malonyl peroxides act both as oxidants and reagents for C?O coupling in reactions with methyl and silyl enol ethers. In the proposed conditions, the oxidative C?O coupling of malonyl peroxides with enol ethers selectively proceeds, bypassing the traditional Rubottom hydroxylation of enol ethers by peroxides. It was observed that the oxidative [5+2] cycloaddition of malonyl peroxides and enol ethers is the key stage of the discovered process. Oxidative C?O coupling of silyl enol ethers leads to the formation of α-acyloxyketones with a free carboxylic acid group. A specially developed preparative one-pot procedure transforms ketones via silyl enol ethers formation and the following coupling into α-acyloxyketones with yields 35–88%. The acid-catalyzed coupling with methyl enol ethers gives remarkable products while retaining the easily oxidizable enol fragment. Furthermore, these molecules contain a free carboxylic acid group, thus these nontrivial products contain two usually incompatible acid and enol ether groups. (Figure presented.).

Umpolung Strategy for Synthesis of β-Ketonitriles through Hypervalent Iodine-Promoted Cyanation of Silyl Enol Ethers

An efficient method to synthesize β-ketonitriles from silyl enol ethers by an umploung hypervalent iodine(III)-CN species generated in situ from PhIO/BF3·Et2O/TMSCN has been developed for the first time. This method can be applied to structurally diverse aromatic and aliphatic substrates and further extended to preparation of bioactive compounds like 5-aminopyrazole and 5-aminoisoxazole.