94286-14-3Relevant academic research and scientific papers
An Extremely Mild Acetate Pyrolysis Reaction. Novel Synthesis and X-Ray Structure Determination of 1-Azaspiroundecane Derivatives
Holmes, Andrew B.,Raithby, Paul R.,Russell, Keith,Stern, Edward S.,Stubbs, Michael E.,Wellard, Nicholas K.
, p. 1191 - 1192 (1984)
The azaspiro oxo-urethane (4), readily available from naphthalene, is reduced to the amino-alcohol (5) whose diacetate (6), the structure of which was determined by X-ray crystallography, undergoes acetate elimination in refluxing toluene to yield the N-acetylazaspiroundecene (7).
FORMAL SYNTHESIS OF (+/-)-PERHYDROHISTRIONICOTOXIN
Holmes, Andrew B.,Russell, Keith,Stern, Edward S.,Stubbs, Michael E.,Wellard, Nicolas K.
, p. 4163 - 4166 (2007/10/02)
The syntheses of 1-benzyl-7-butyl-1-azaspirocycloundec-7-ene (14) a formal precursor of perhydrohistrionicotoxin (2) and the thermodynamically preferred exocyclic isomer (13) in six steps from the readily available N-benzyloxycarbonyl-10-amino-Δsup
