168133-91-3

Usage

Chemical structure

A unique structure with a spiro central ring system and a phenylmethyl group.

Classification

Belongs to the class of spirolactams, which are heterocyclic compounds.

Functional groups

Contains a carbonyl group (C=O) and a phenylmethyl group (C6H5-CH2-).

Potential reactivity

The presence of the phenylmethyl group adds to the molecule's complexity and may influence its reactivity.

Applications

May have uses in the pharmaceutical and agrochemical industries, as well as in organic synthesis and chemical research.

Further exploration

More research is needed to fully understand its capabilities and implications in various fields.

Upstream product

• 100-39-0 benzyl bromide 
• 94273-08-2 1-Aza-spiro[5.5]undecan-7-one 
• 94283-46-2 N-benzyloxycarbonyl-10-amino-Δ^1,9-octalin 
• 94286-14-3 7-Oxo-1-aza-spiro[5.5]undec-2-ene-1-carboxylic acid benzyl ester 
• 94273-10-6 7-Oxo-1-aza-spiro[5.5]undecane-1-carboxylic acid benzyl ester 
• 1044869-65-9 N-benzyl-2-(4-chlorobutyl)-2-cyanopiperidine 
• 94283-45-1 1,3,4,5,6,7-hexahydro-2H-[4a]naphthylamine 
• 15862-72-3 ethyl pipecolate 
• 4043-87-2 pipecolic Acid 
• 168133-90-2 (+/-)-ethyl 1-benzyl-2-(4-ethoxycarbonylbutyl) pipecolinate 
• 1026821-49-7 1-Benzyl-7-oxo-1-aza-spiro[5.5]undecane-8-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Cyclization via carbolithiation of α-amino alkyllithium reagents

(Chemical Equation Presented) We report a new route to tertiary α-amino stereocenters by sequential alkylation of α-amino nitriles followed by reductive lithiation of the nitrile and cycllzation onto an alkene. Reductive lithiation of α-amino nitriles usi

A new and convenient synthesis of 1-benzyl-1-azaspiro [5.5] undecan-7-one: A formal synthesis of (±)-perhydrohistrio-nicotoxin

A rapid, three-step synthesis of the title compound 3 in 40% overall yield from (±)-pipecolinic acid, is described.

FORMAL SYNTHESIS OF (+/-)-PERHYDROHISTRIONICOTOXIN

The syntheses of 1-benzyl-7-butyl-1-azaspirocycloundec-7-ene (14) a formal precursor of perhydrohistrionicotoxin (2) and the thermodynamically preferred exocyclic isomer (13) in six steps from the readily available N-benzyloxycarbonyl-10-amino-Δsup