94286-29-0Relevant academic research and scientific papers
The Diastereoselectivity of Electrophilic Attack on Trigonal Carbon Adjacent To a Stereogenic Centre: Diastereoselective Alkylation and Protonation of Open-chain Enolates Having a Stereogenic Centre Carrying a Silyl Group at the β Position
Crump, Roger A. N. C.,Fleming, Ian,Hill, John H. M.,Parker, David,Reddy, N. Laxma,Waterson, David
, p. 3277 - 3294 (2007/10/02)
The alkylation and protonation of enolates having a β-silyl group, prepared by conjugate addition of a silyl-cuprate reagent to enone systems, are almost always highly diastereoselective in the sense 3 in a wide variety of reactions.The effects of varying
Observations on Various Silyl-Cuprate Reagents
Fleming, Ian,Newton, Trevor W.
, p. 1805 - 1808 (2007/10/02)
The mixed silyl-cuprate reagent (6), made from 1 equiv. of methyl-lithium, 1 equiv. of phenyldimethylsilyl-lithium, and 1 equiv. of copper(I) cyanide, reacts with 3-methylcyclohexenone (7), with methyl cinnamate (9), with 1-vinylcyclohexyl acetate (11), a
