30262-97-6

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 104-55-2 3-phenyl-propenal 
• 14371-10-9 (E)-3-phenylpropenal 
• 30263-03-7 3-Phenyl-3-(trimethylsilyl)-1-propanol 
• 54198-32-2 1-(N-Methyl-N-phenylamino)-3-phenyl-3-trimethylsilyl-1-propene 
• 102-92-1 cinnamoyl chloride 
• 37935-78-7 ((Z)-1,3-Bis-trimethylsilanyl-3-trimethylsilanyloxy-allyl)-benzene 
• 94286-29-0 methyl (RS)-3-phenyl-3-trimethylsilylpropanoate 
• 37935-79-8 3-phenyl-3-(trimethylsilyl)-propionyltrimethylsilane 

Downstream Products

• 35802-50-7 3-phenyl-3-(trimethylsilyl)prop-1-ene 
• 69562-10-3 1-phenyl-3-phenylseleno-1-propene 
• 129178-71-8 3-Phenyl-2-(phenylseleno)-3-(trimethylsilyl)propanal 
• 129178-79-6 3-Phenyl-2-(phenylseleno)-3-(trimethylsilyl)-1-propanol 
• 18192-48-8 trimethyl(1-phenylbut-3-en-1-yl)silane 
• 129178-75-2 (Z)-3-Phenyl-1-(trimethylsilyloxy)-3-(trimethylsilyl)-1-propene 
• 129178-82-1 (E)-3-Phenyl-1-(trimethylsilyloxy)-3-(trimethylsilyl)-1-propene 
• 30263-03-7 3-Phenyl-3-(trimethylsilyl)-1-propanol 

Relevant academic research and scientific papers

Synthesis of β-silylated olefins from α,β-unsaturated aldehydes and ketones

α,β-Unsaturated aldehydes and ketones such as phorone, benzalacetone, benzalacetophenone, 4-(2-furyl)-3-buten-4-one and β-ionone, react with TMS-Cl in the presence of Li in THF to give conjugated β-silylated enoxysilanes. Hydrolysis of this compounds in a

REGIO- AND STEREOSELECTIVE SYNTHESIS OF ALLYLTRIMETHYLSILANES VIA KRIEF-REICH ELIMINATION IN β-SELENO-γ-SILYL ALCOHOLS

The synthesis of (E)-allyltrimethylsilanes by regio- and stereocontrolled pathways is described based on the preference for Krief-Reich elimination over silicon-controlled rearrangement in β-seleno-γ-silyl alcohols, readily available from α-selenoaldehydes, 10 - 12.Usefulness of this protocol for the introduction of the allylsilane function α to the carbonyl group in cycloalkanones as well as for the preparation of unsymmetrically substituted allylsilanes is also reported.

THE REACTIONS OF COMBINED ORGANOCUPRATE-CHLOROTRIMETHYLSILANE REAGENTS WITH CONJUGATED CARBONYL COMPOUNDS

Organocuprates and chlorotrimethylsilane are compatible as separate species in THF or ether solution at -50 to -78o, and in combination can both accelerate and improve 1,4-addition reactions with conjugated carbonyl compounds.