943448-07-5Relevant academic research and scientific papers
Regioselective Iridium-Catalyzed Asymmetric Monohydrogenation of 1,4-Dienes
Liu, Jianguo,Krajangsri, Suppachai,Singh, Thishana,De Seriis, Giulia,Chumnanvej, Napasawan,Wu, Haibo,Andersson, Pher G.
, p. 14470 - 14475 (2017/10/24)
A highly efficient regio- and enantioselective monohydrogenation of 1,4-dienes has been realized using an iridium catalyst with a chiral N,P-ligand under mild conditions. The substrate scope was studied and included both unfunctionalized as well as functionalized substituents on the meta- or para-position. Substrates having substituents with functionalities such as silyl protected alcohols or ketals were monohydrogenated in high regioselectivity and high enantiomeric excess (up to 98% ee).
Catalytic enantioselective conjugate allylation of unsaturated methylidene ketones
Brozek, Laura A.,Sieber, Joshua D.,Morken, James P.
, p. 995 - 997 (2011/05/15)
The use of unsaturated methylidene ketones in catalytic conjugate allylations allows a significant expansion in substrate scope and, with appropriate chiral ligands, occurs in a highly enantioselective fashion.(Figure Presented)
An Approach to the Synthesis of Stenine
Zhu, Liang,Lauchli, Ryan,Loo, Mandy,Shea, Kenneth J.
, p. 2269 - 2271 (2008/02/05)
A type 2 N-acylnitroso intramolecular Diels-Alder reaction followed by reductive N - O bond cleavage formed the B and C rings of the Stemona alkaloid stenine. Further elaboration provided the functionalized tricyclic core.
