94348-39-7Relevant academic research and scientific papers
Synthesis of unsymmetrical ketones by applying visible-light benzophenone/nickel dual catalysis for direct benzylic acylation
Krach, Patricia E.,Dewanji, Abhishek,Yuan, Tingting,Rueping, Magnus
supporting information, p. 6082 - 6085 (2020/06/18)
Herein, we report a dual catalytic system for the direct benzylic C-H acylation reaction furnishing a variety of unsymmetrical ketones. A benzophenone-derived photosensitizer combined with a nickel catalyst has been established as the catalytic system. Both acid chlorides and anhydrides are able to acylate the benzylic position of toluene and other methylbenzenes. The method offers a valuable alternative to late transition metal catalyzed C-H acylation reactions.
