94407-05-3

Basic information

• Product Name: 2-[4-hydroxy-3-nitro-phenyl]-1,3-dioxane
• Synonyms: 2-[4-hydroxy-3-nitro-phenyl]-1,3-dioxane
• CAS NO: 94407-05-3
• Molecular Weight: 225.201
• Mol File: 94407-05-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-[4-hydroxy-3-nitro-phenyl]-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-hydroxy-3-nitro-phenyl]-1,3-dioxane(94407-05-3)
• EPA Substance Registry System: 2-[4-hydroxy-3-nitro-phenyl]-1,3-dioxane(94407-05-3)

Safety Data

• Hazardous Substances Data: 94407-05-3(Hazardous Substances Data)

Upstream product

• 3011-34-5 4-hydroxy-3-nitrobenzaldehyde 
• 504-63-2 trimethyleneglycol 

Downstream Products

• 200195-15-9 3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbaldehyde 
• 897545-07-2 2-Amino-4-[1,3]dioxan-2-yl-phenol 

Relevant articles and documents

A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: Discovery of a potential atypical antipsychotic agent

As part of a program to develop dopamine D4 antagonists for the treatment of schizophrenia, we discovered a series of 6- and 7- (phenylpiperazinyl)- and -(phenylpiperidinyl)methylbenzoxazinones through mass screening of our compound library. A structure-a

Phenylene derivatives and anti-allergic use thereof

Novel phenylene derivatives shown by the general formula STR1 wherein A represents a hydrogen atom, a phenyl group or a phenoxy group, n represents an integer of 3 to 10, R1 represents a hydrogen atom or a lower alkoxy group, X1 represents --CH2 CH2 --, --CH=CH--, --CONH--, B represents STR2 (wherein R2 represents a hydrogen atom, a halogen atom, a nitro group, etc.), STR3 (wherein R3 represents a hydrogen atom, a hydroxyl group or a lower alkoxy group), X2 represents --CH=CH--, --CH2 CH2 --, etc. and D represents a carboxy group, a lower alkoxycarbonyl group or STR4 which are useful as drugs, particularly SRS-A (slow reacting substance of anaphylaxis) antagonist, i.e. they are useful as prophylaxis and treatment for various allergic diseases (e.g. bronchial asthma, allergic rhinitis, urticaria) or, ischemic heart diseases, inflammation, etc. induced by SRS-A.