94430-87-2

Upstream product

• 620-13-3 1-bromomethyl-3-methyl-benzene 
• 18424-77-6 sodium diethyl methylmalonate 
• 6432-79-7 [(3-methylphenyl)methyl]propanedioic acid diethyl ester 
• 609-08-5 Diethyl methylmalonate 
• 587-03-1 3-methylbenzyl alcohol 
• 620-19-9 1-chloromethyl-3-methyl-benzene 

Downstream Products

• 89044-50-8 2,4,7-trimethyl-2,3-dihydro-1H-inden-1-one 
• 89044-52-0 2,6,7-trimethylindan-1-one 
• 89044-51-9 5,6-dimethyl-2-methyl-1-indanone 
• 73120-63-5 β-(3,6-dimethylphenyl)-α-methylpropionic acid 
• 89044-48-4 2,5-dimethyl-2,3-dihydro-1H-inden-1-one 
• 859192-05-5 α-methyl-β-(3-methylphenyl)propionic acid 
• 853996-58-4 methyl-(3-methyl-benzyl)-malonic acid 

Relevant academic research and scientific papers

Nickel-Catalyzed Benzylic Substitution of Benzyl Esters with Malonates as a Soft Carbon Nucleophile

The nickel-catalyzed benzylic substitution of benzyl alcohol derivatives with a soft carbon nucleophile is extremely rare compared to that with a hard carbon nucleophile. We have achieved the nickel-catalyzed benzylic substitution of benzyl esters with malonates as a soft carbon nucleophile. Primary and secondary benzyl 2,3,4,5,6-pentafluorobenzoates as well as a wide variety of malonate derivatives were well tolerated in the nickel-catalyzed reaction, providing the corresponding alkylation products in 46-86% yields (34 examples). Additionally, we propose a possible reaction mechanism that would undergo via the ??1- A nd ??3-benzylnickel intermediates.

Alcohols having 3-methyl or 3,5-dimethyl or 3,5-dimethylphenyl groups, a process for their preparation and a fragrance composition containing same

2-Methyl-3-(3-methylphenyl)-propan-1-ol, 2-methyl-3-(3,5-dimethylphenyl)-propan-1-ol, 1-(3-methylphenyl)-2-methylbutan-3-ol and 1-(3,5-dimethylphenyl)-2-methylbutan-3-ol, their preparation and use as fragrances.

Carbon-13 Nuclear Magnetic Resonance Spectra of Pterosin-Sesquiterpenes and Related Indan-1-one Derivatives

Methyl derivatives of indan-1-one were prepared as models to aid in interpreting the carbon-13 nuclear magnetic resonance ((13)C-NMR) spectra of pterosin-sesquiterpenes which were isolated from bracken fern, Pteridium aquilinum var. latiusculum.The chemical shifts of the carbons of the methylindan-1-ones were assigned by the proton decoupling technique.All the (13)C-NMR signals of the pterosin-sesquiterpenes were assigned by means of selective proton decouplings, and from the (13)C-(1)H long-range couplings and (13)C chemical shifts of the model compounds.Keywords - indan-1-one derivative; methylindan-1-one; pterosin-sesquiterpene; methylindan-1-one synthesis; (1)H-NMR; (13)C-NMR; selective decoupling; C-H decoupling