89044-48-4

Basic information

• Product Name: 1H-Inden-1-one, 2,3-dihydro-2,5-dimethyl-
• CAS NO: 89044-48-4
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Mol File: 89044-48-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Inden-1-one, 2,3-dihydro-2,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Inden-1-one, 2,3-dihydro-2,5-dimethyl-(89044-48-4)
• EPA Substance Registry System: 1H-Inden-1-one, 2,3-dihydro-2,5-dimethyl-(89044-48-4)

Safety Data

• Hazardous Substances Data: 89044-48-4(Hazardous Substances Data)

Usage

General Description

1H-Inden-1-one, 2,3-dihydro-2,5-dimethyl- is a chemical compound with the molecular formula C13H14O. It is a colorless to pale yellow liquid with a floral, woody odor. 1H-Inden-1-one, 2,3-dihydro-2,5-dimethyl- is commonly used as a fragrance ingredient in perfumes and personal care products. It is also used in the synthesis of pharmaceuticals and as a chemical intermediate in the manufacturing of other organic compounds. Additionally, 1H-Inden-1-one, 2,3-dihydro-2,5-dimethyl- has potential applications in the development of new materials and as a chemical building block for the production of specialty chemicals. Overall, this compound has a range of industrial and commercial uses due to its unique odor and chemical properties.

Upstream product

• 859192-05-5 α-methyl-β-(3-methylphenyl)propionic acid 
• 87808-49-9 2-bromo-4-methyl-benzoic acid methyl ester 
• 959631-88-0 methyl 2-allyl-4-methylbenzoate 
• 94430-87-2 diethyl (3-methylphenylmethyl)methylmalonate 
• 620-13-3 1-bromomethyl-3-methyl-benzene 

Downstream Products

• 140841-04-9 3,4-dihydro-3,6-dimethyl-2H-1-benzopyran-2-one 
• 285977-85-7 (+/-)-2,3-dihydro-2,5-dimethyl-1H-indene-2-methanol 
• 285977-87-9 (+)-(2S)-2,3-dihydro-2,5-dimethyl-1H-indene-2-methanol 
• 285978-03-2 2-(hydroxymethyl)-2,5-dimethyl-2,3-dihydro-1H-inden-1-one 

Relevant articles and documents

Nickel-Catalyzed Domino Heck-Type Reactions Using Methyl Esters as Cross-Coupling Electrophiles

While esters are frequently used as traditional electrophiles in substitution chemistry, their application in cross-coupling chemistry is still in its infancy. This work demonstrates that methyl esters can be used as coupling electrophiles in Ni-catalyzed Heck-type reactions through the challenging cleavage of the C(acyl)?O bond under relatively mild reaction conditions at either 80 or 100 °C. With the σ-NiII intermediate generated from the insertion of acyl NiII species into the tethered C=C bond, carbonyl-retentive products were formed by domino Heck/Suzuki–Miyaura coupling and Heck/reduction pathways when organoboron and mild hydride nucleophiles are used.

Rh-catalyzed reagent-free ring expansion of cyclobutenones and benzocyclobutenones

Here we report a reagent-free rhodium-catalyzed ring-expansion reaction via C-C cleavage of cyclobutenones. A variety of poly-substituted cyclopentenones and 1-indanones can be synthesized from simple cyclobutenones and benzocyclobutenones. The reaction condition is near pH neutral without additional oxidants or reductants. The potential for developing a dynamic kinetic asymmetric transformation of this reaction has also been demonstrated. Further study supports the proposed pathway involving Rh-insertion into the cyclobutenone C-C bond, followed by β-hydrogen elimination, olefin insertion and reductive elimination.

Carbon-13 Nuclear Magnetic Resonance Spectra of Pterosin-Sesquiterpenes and Related Indan-1-one Derivatives

Methyl derivatives of indan-1-one were prepared as models to aid in interpreting the carbon-13 nuclear magnetic resonance ((13)C-NMR) spectra of pterosin-sesquiterpenes which were isolated from bracken fern, Pteridium aquilinum var. latiusculum.The chemical shifts of the carbons of the methylindan-1-ones were assigned by the proton decoupling technique.All the (13)C-NMR signals of the pterosin-sesquiterpenes were assigned by means of selective proton decouplings, and from the (13)C-(1)H long-range couplings and (13)C chemical shifts of the model compounds.Keywords - indan-1-one derivative; methylindan-1-one; pterosin-sesquiterpene; methylindan-1-one synthesis; (1)H-NMR; (13)C-NMR; selective decoupling; C-H decoupling