944316-52-3

Upstream product

• 944317-25-3 (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[(3-bromo-6-chloropyridin-2-yl)methyl]-4-methyl-1,3-oxazolidin-2-one 
• 42753-71-9 5-bromo-6-methyl-pyridin-2-ylamine 
• 934842-18-9 methyl 4-(3-iodo-4-methoxyphenyl)-3-methylbenzoate 
• 132606-40-7 3-bromo-6-chloro-2-methyl-pyridine 
• 547756-20-7 3-bromo-2-(bromomethyl)-6-chloropyridine 

Relevant academic research and scientific papers

CETP INHIBITORS

Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), B is a cyclic group other than phenyl, and B has a cyclic substituent at a position that is ortho to the position at which B is connected to the remainder of the structure of Formula (I). The 5-membered ring of Formula (I) has a second cyclic substituent in addition to B.