944900-06-5 Usage
Uses
Used in Pharmaceutical and Agrochemical Industries:
2-Chloro-6-(trifluoromethyl)nicotinaldehyde is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals for its ability to contribute to the development of new drugs and pesticides. Its unique chemical structure allows it to be a key component in the creation of molecules with specific therapeutic or pesticidal properties.
Used in Chemical Research:
As a reagent, 2-Chloro-6-(trifluoromethyl)nicotinaldehyde is utilized in chemical research to facilitate various reactions and to explore its chemical properties and potential applications in the synthesis of new compounds.
Used in Organic Compound Production:
2-Chloro-6-(trifluoromethyl)nicotinaldehyde also serves as a building block in the production of other organic compounds, where its specific functional groups and structural features are leveraged to construct more complex molecules.
Used in Enzyme Inhibition:
2-Chloro-6-(trifluoromethyl)nicotinaldehyde is known to be a potent inhibitor of the enzyme mitochondrial aldehyde dehydrogenase. It is used as a potential candidate for the treatment of alcoholism due to its ability to interfere with the metabolism of alcohol, and for certain types of cancer where its inhibitory effect on the enzyme could have therapeutic benefits.
However, it is important to consider the high toxicity and potential environmental impact of 2-Chloro-6-(trifluoromethyl)nicotinaldehyde when handling and using this chemical, ensuring proper safety measures and disposal methods are in place.
Check Digit Verification of cas no
The CAS Registry Mumber 944900-06-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,0 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 944900-06:
(8*9)+(7*4)+(6*4)+(5*9)+(4*0)+(3*0)+(2*0)+(1*6)=175
175 % 10 = 5
So 944900-06-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H3ClF3NO/c8-6-4(3-13)1-2-5(12-6)7(9,10)11/h1-3H
944900-06-5Relevant academic research and scientific papers
Discovery of novel chiral diazepines as bombesin receptor subtype-3 (BRS-3) agonists with low brain penetration
Matsufuji, Tetsuyoshi,Shimada, Kousei,Kobayashi, Shozo,Kawamura, Asuka,Fujimoto, Teppei,Arita, Tsuyoshi,Hara, Takashi,Konishi, Masahiro,Abe-Ohya, Rie,Izumi, Masanori,Sogawa, Yoshitaka,Nagai, Youko,Yoshida, Kazuhiro,Takahashi, Hisashi
, p. 750 - 755 (2014/02/14)
The discovery and optimization of a novel series of BRS-3 agonists are described. We explored a potent BRS-3 agonist with low brain penetration to avoid an adverse effect derived from central nervous system exposure. Through the derivatization process, chiral diazepines 9f and 9g were identified as possessing low brain penetration as well as potent in vitro activity against human and mouse BRS-3s.
COMPOUNDS WITH NEMATICIDAL ACTIVITY
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, (2013/05/22)
The present invention relates to the use of known pyridyl carboxamide derivatives and novel pyridyl carboxamide derivatives as nematicides, compositions containing such compounds and methods for the control of nematodes.
FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE
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Page/Page column 105-106, (2010/08/08)
The invention relates to thiazole compounds of Formula (I) and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.
7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES
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Page/Page column 141, (2010/07/09)
Compounds of Formula I: (I) in which A, A1, R1, R7a, R7b, R8 and R10 have the meanings given in the specification, are DP2 receptor inhibitors useful in the treatment of useful in the treat
