944900-15-6

Basic information

• Product Name: 1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone
• Synonyms: 1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone
• CAS NO: 944900-15-6
• Molecular Formula: C8H5ClF3NO
• Molecular Weight: 223.5796096
• Mol File: 944900-15-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone(944900-15-6)
• EPA Substance Registry System: 1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone(944900-15-6)

Safety Data

• Hazardous Substances Data: 944900-15-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone is used as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure contributes to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone also serves as an intermediate in the production of agrochemicals, playing a crucial role in the development of chemicals used in the agricultural industry for pest and disease control.
Used as a Reagent in Organic Synthesis:
1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone is utilized as a reagent in organic synthesis, facilitating various chemical reactions and contributing to the creation of new organic compounds.
Used as a Building Block in Pharmaceutical R&D:
In the realm of research and development within the pharmaceutical industry, 1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone acts as a building block, enabling the design and synthesis of novel drug candidates with potential therapeutic benefits.
Used as a Solvent in Chemical Reactions and Processes:
Furthermore, 1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone can be employed as a solvent in chemical reactions and processes, providing a medium for reactions to occur and potentially enhancing the efficiency of these processes.
Used in the Study of Pharmacological Properties:
Due to its potential as a bioactive molecule, 1-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)ethanone has been studied for its pharmacological properties, which may lead to the discovery of new treatments and therapies in the medical field.

Upstream product

• 116548-05-1 3-acetyl-6-(trifluoromethyl)-2(1H)-pyridinone 
• 280566-45-2 2-chloro-6-(trifluoromethyl)pyridine-3-carboxylic acid 
• 1005171-62-9 C₉H₈ClF₃N₂O₂ 
• 676-58-4 methylmagnesium chloride 

Downstream Products

• 1080675-91-7 1-(2-Phenylamino-6-trifluoromethyl-pyridin-3-yl)-ethanone 
• 1080674-73-2 C₂₇H₂₂F₃N₃O₅ 
• 1080674-72-1 C₂₅H₁₉F₃N₂O₅S 
• 358780-14-0 1-[(6-trifluoromethyl)-pyridine-3-yl]ethan-1-one 

Relevant articles and documents

PROCESS FOR THE MANUFACTURE OF 2-SUBSTITUTED-5-(1-METHYLTHIO)ALKYLPYRIDINES

Process for the manufacture of 2-substituted-5-(1-methylthio)alkylpyridines and a process for the manufacture of agriculturally or pharmaceutically active substances comprising the process for the manufacture of 2-substituted-5-(1- methylthio)alkylpyridines.

Discovery of a novel series of 4-quinolone JNK inhibitors

A novel series of highly selective JNK inhibitors based on the 4-quinolone scaffold was designed and synthesized. Structure based drug design was utilized to guide the compound design as well as improvements in the physicochemical properties of the series. Compound (13c) has an IC50 of 62/170 nM for JNK1/2, excellent kinase selectivity and impressive efficacy in a rodent asthma model.