944904-26-1 Usage
Uses
Used in Chemical Synthesis:
7-Bromo-3-iodoindazole is used as a key ingredient in the synthesis of more complex chemical compounds, particularly in research and manufacturing processes. Its unique structure and the presence of iodine and bromine atoms make it a valuable component in creating new molecules with specific properties and applications.
Used in Halogen Exchange Reactions:
In the field of organic chemistry, 7-Bromo-3-iodoindazole is employed as a reactant in halogen exchange reactions. Its iodine and bromine atoms allow for the substitution of halogens, leading to the formation of new compounds with altered properties. This makes it a useful tool in the development of novel chemical entities and materials.
Used in Scientific Research:
7-Bromo-3-iodoindazole is utilized by the scientific community for various research purposes, including the study of its chemical properties, reactivity, and potential applications. Its unique structure and functional groups make it an interesting subject for exploration in the fields of chemistry, materials science, and related disciplines.
Check Digit Verification of cas no
The CAS Registry Mumber 944904-26-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,0 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 944904-26:
(8*9)+(7*4)+(6*4)+(5*9)+(4*0)+(3*4)+(2*2)+(1*6)=191
191 % 10 = 1
So 944904-26-1 is a valid CAS Registry Number.
944904-26-1Relevant articles and documents
CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
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, (2022/01/08)
Provided herein are piperidine dione compounds having the following structure: wherein R1, R2, R3, R4, L, V, X, a and m are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.
A novel series of indazole-/indole-based glucagon receptor antagonists
Lin, Songnian,Zhang, Fengqi,Jiang, Guoqiang,Qureshi, Sajjad A.,Yang, Xiaodong,Chicchi, Gary G.,Tota, Laurie,Bansal, Alka,Brady, Edward,Trujillo, Maria,Salituro, Gino,Miller, Corey,Tata, James R.,Zhang, Bei B.,Parmee, Emma R.
, p. 4143 - 4147 (2015/11/03)
A novel, potent series of glucagon receptor antagonists (GRAs) was discovered. These indazole- and indole-based compounds were designed on an earlier pyrazole-based GRA lead MK-0893. Structure-activity relationship (SAR) studies were focused on the C3 and C6 positions of the indazole core, as well as the benzylic position on the N-1 of indazole. Multiple potent GRAs were identified with excellent in vitro profiles and good pharmacokinetics in rat. Among them, GRA 16d was found to be orally active in blunting glucagon induced glucose excursion in an acute glucagon challenge model in glucagon receptor humanized (hGCGR) mice at 1, 3 and 10 mg/kg (mpk), and significantly lowered acute glucose levels in hGCGR ob/ob mice at 3 mpk dose.
