94532-48-6Relevant academic research and scientific papers
Redox-neutral α-C-H bond functionalization of secondary amines with concurrent C-P bond formation/N-alkylation
Das, Deepankar,Seidel, Daniel
, p. 4358 - 4361 (2013/09/24)
Redox-neutral formation of C-P bonds in the α-position of amines was achieved via a process that features a combination of an oxidative α-C-H bond functionalization and a reductive N-alkylation. Benzoic acid functions as an efficient catalyst in this three-component reaction of cyclic secondary amines, aldehydes and phosphine oxides to provide rapid access to α-amino phosphine oxides not easily accessible by classic Kabachnik-Fields reactions.
Copper-catalyzed C-P coupling through decarboxylation
Hu, Jie,Zhao, Ning,Yang, Bin,Wang, Ge,Guo, Li-Na,Liang, Yong-Min,Yang, Shang-Dong
supporting information; experimental part, p. 5516 - 5521 (2011/06/21)
An acid for a phosphine: A versatile protocol for preparation of various di(phenyl)phosphoryl oxides was developed by copper-catalyzed decarboxylative coupling of alkenyl, alkynyl carboxylic acids, and N-benzylproline, respectively, with R2P(O)
2-(DIPHENYLPHOSPHINOYL) PYRROLIDINES; VERSATILE REAGENTS FOR THE SYNTHESIS OF HETEROCYCLIC ENAMINES AND ENAMIDES.
Bakker, B. H.,A-Lim, D. S. Tjin,Gen, A. van der
, p. 4259 - 4262 (2007/10/02)
A method is described for the preparation of N-substituted 2-(diphenylphosphinoyl) pyrrolidines.Application of these phosphine oxides in the Horner-Wittig reaction affords heterocyclic enamines and enamides in good yields.
