94540-11-1

Usage

Uses

Used in Pharmaceutical Industry:
(2-bromophenyl)(naphthalen-1-yl)methanone is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs and medications.
Used in Organic Synthesis:
In the field of organic chemistry, (2-bromophenyl)(naphthalen-1-yl)methanone serves as a valuable intermediate for the synthesis of a wide range of organic compounds. Its versatility makes it a useful building block for creating complex molecules with specific properties and functions.
It is important to handle (2-bromophenyl)(naphthalen-1-yl)methanone with caution, as it may be harmful if swallowed, inhaled, or comes into contact with skin or eyes. Proper safety measures should be taken to minimize any potential risks associated with its use.

Upstream product

• 2042-37-7 o-cyanobromobenzene 
• 703-55-9 1-naphthylmagnesiumbromide 
• 91-20-3 naphthalene 
• 7154-66-7 2-bromobenzoic acid chloride 
• 1333506-86-7 (2-bromophenyl)(naphthalen-1-yl)methanol 
• 6630-33-7 ortho-bromobenzaldehyde 
• 90-11-9 1-Bromonaphthalene 

Downstream Products

• 1023896-55-0 2-(1-naphthoyl)benzonitrile 
• 94255-33-1 7-<2-Brom-phenyl>-perinaphthenon 
• 99001-32-8 1-<2-Brom-phenyl>-3-benz(e)-inden-3-on 
• 87829-14-9 1-(1-naphthyl)-1-phenylethylene 

Relevant academic research and scientific papers

Synthesis of naphthalene ring derivatives and Benzoheterocycles the method of the compound

The invention discloses a method for synthesizing naphthalene derivative and benzo-heterocycle compounds. The method is realized by promoting a reaction similar to Mortia-Baylis-Hillman between aryl aldehyde having alpha, beta-unsaturated ester on ortho-position and ketone compounds under the catalysis action of tertiary amine and tertiary phosphine organic small molecular catalysts, so as to remove a molecule of H2O, so that the naphthalene derivative or benzo-heterocycle compounds are generated. The method disclosed by the invention is simple in operation step, cheap and easily available in adopted catalysts and harmless to environment, and a series of naphthalene derivative and benzo-heterocycle compounds are synthesized with relatively high yield.

Method for synthesizing axial chiral biaryl compounds by utilizing tertiary amine small organic molecules

The invention discloses a method for synthesizing axial chiral biaryl compounds by utilizing tertiary amine small organic molecules. According to the method, similar Mortia-Baylis-Hillman reactions in molecules are utilized, and chiral prosthetic groups are used as inducing groups, so that axial chiral biaryl compounds are asymmetrically constructed in one step. The method for synthesizing the axial chiral biaryl compounds has the advantages of environmental friendliness, no use of expensive metal catalysts, atom economy and easiness in modification of substrates, the yield of the biaryl compounds as products can reach 80% to 97%, and a De value reaches 70% to 80%. The invention provides a green environment-friendly way for various preparations of the axial chiral biaryl compounds.