945491-75-8

Upstream product

• 112-82-3 hexadecanyl bromide 
• 945491-73-6 3-O-benzyl-1-O-hexadecanoyl-2-O-hexadecyl-sn-glycerol 
• 573673-85-5 (R)-3-(benzyloxy)-2-(hexadecyloxy)propan-1-ol 
• 945491-72-5 1-O-allyl-3-O-benzyl-2-O-hexadecyl-sn-glycerol 
• 945491-74-7 (S)-2-(hexadecyloxy)-3-hydroxypropyl palmitate 
• 108549-21-9 benzyl-N,N,N',N'-tetraisopropylphosphorodiamidite 

Downstream Products

• 1034620-47-7 C₁₁₀H₁₄₅O₁₇P 
• 1034916-22-7 3,4,5-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-2-O-(2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)-1-O-(1-O-hexadecanoyl-2-O-hexadecyl-sn-glycero-3-benzylphosphoryl)-D-myo-inositol 
• 1034620-22-8 3,4,5,6-tetra-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1-O-hexadecanoyl-2-O-hexadecyl-sn-glycero-3-benzylphosphoryl)-D-myo-inositol 
• 1034620-37-5 1,3-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1-O-hexadecanoyl-2-O-hexadecyl-sn-glycero-3-benzyIphosphoryl)glycerol 

Relevant academic research and scientific papers

ANALOGUES OF PHOSPHATIDYLINOSITOL MANNOSIDES

The invention relates to compounds which are immunomodulatory compounds and, in particular, can induce IL-12 secretion. The invention also relates to compositions containing the compounds, precursors, and prodrugs of these compounds, use of these compounds as adjuvants in combination with vaccines, and use of these compounds for treatment of diseases or conditions relating to infection, atopic disorders, or cancer.

Phosphatidylinositol mannoside ether analogues: Syntheses and interleukin-12-inducing properties

(Chemical Equation Presented) Phosphatidylinositol mannosides (PIMs) isolated from mycobacteria have been identified as an important class of glycolipids with significant immune modulating properties. We present here the syntheses of phosphatidylinositol