945565-67-3

Upstream product

• 945565-66-2 (1'R,2'S,4'S,5'S)-1-hydroxymethyl-4-(2-iodo-6-methylaminopurin-9-yl)-bicyclo[3.1.0]hexan-2-ol 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 452335-24-9 (1R,2S,4R,5S)-(2-acetoxy-4-hydroxybicyclo[3.1.0]hex-1-yl)methyl acetate 
• 10310-21-1 2-Amino-6-chloropurin 
• 945565-65-1 (1'R,2'S,4'S,5'S)-acetic acid 1-acetoxymethyl-4-(6-chloro-2-iodopurin-9-yl)-bicyclo[3.1.0]hex-2-yl ester 

Downstream Products

• 945565-68-4 (1'R,2'S,4'S,5'S)-phosphoric acid 1-[(bis-(4-methoxyphenyl)-phenylmethoxy)methyl]-4-(2-iodo-6-methylaminopurin-9-yl)-bicyclo[3.1.0]hex-2-yl ester di-tert-butyl ester 

Relevant academic research and scientific papers

P2Y1 antagonists: Combining receptor-based modeling and QSAR for a quantitative prediction of the biological activity based on consensus scoring

P2Y1 is an ADP-activated G protein-coupled receptor (GPCR). Its antagonists impede platelet aggregation in vivo and are potential antithrombotic agents. Combining ligand and structure-based modeling we generated a consensus model (LIST-CM) corr